The Black Stars narrowed their chances of qualifying for the 2018 FIFA World Cup after drawing 1-1 with Congo last Friday at the Babayara Sports Stadium.
The four-time Africa Champions had to toil to earn a point in front of their home fans after going down in the first half.
Thievy Bifouma scored for Congo in 17 minutes before Thomas Partey drew level with 5 minutes left on the clock.
The result puts Ghana in a difficult position to make it to Russia 2018 as they lie third with just 2 points from a possible nine.
The team will now take on Congo in the reverse fixture today away from home.
Coach Kwesi Appiah and his men needs nothing less than a win to revive their chances.
The Black Stars will be heading into the game without key players Asamoah Gyan, Andre Ayew, Jordan Ayew, Harrison Afful and John Boye who have all picked up various injuries. Jordan Ayew is reported to suffering from a stomach upset hence ruling him out of the clash.
Ghana will also need to hope for a favorable result between Uganda and Egypt who occupy the first and second positions respectively.
By Frank Darkwah