Black stars winger Christian Atsu could not complete the team’s training session on Wednesday after complaining of a thigh injury.
The Newcastle United star made himself available for the match despite concerns about his fitness.
Atsu could not last the entire training and had to pull out midway.
He will be assessed by the medical team.
The 25-year-old joined Captain Asamoah Gyan as the two players doubtful for the game against Egypt on Sunday.