Kotoko will face Cameroonian Club Coton Sport in the CAF Confederation Cup playoffs.
The Reds were paired with the Cameroonian giants in a draw held on Friday.
Kotoko made it to the final qualifying round after eliminating Kariobangi Sharks from Kenya.
Coton Sport on the other hand got demoted to the Confederation Cup after exiting the Caf Champions League having lost 3-2 on aggregate to Egyptian side Ismaily.
Kotoko remains Ghana’s sole representative in Africa this term.
By Frank Darkwah